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Hydroxyamphetamine

Properties, data and information sources.

 

Contents

Hydroxyamphetamine is an organic chemical compound from the group of substituted phenethylamine derivatives, as well as a derivative and a metabolite of the stimulant amphetamine.

 

Names and Identifiers

Name
Hydroxyamphetamine
Formula
C9H13NO
Molar mass
151.209 (g/mol)
CAS registry number
103-86-6
EC number EINECS
203-152-8
InChI Key
GIKNHHRFLCDOEU-UHFFFAOYSA-N

Systematic name
4-(2-Aminopropyl)phenol

Other names, synonyms
DL-p-Hydroxyamphetamine; DL-4-Hydroxyamphetamine; Hydroxyamfetamine; p-(2-Aminopropyl)phenol; 1-p-Hydroxyphenyl-2-propylamine; 2-Amino-1-(p-hydroxyphenyl)propane; p-Hydroxy-α-methylphenethylamine; 4-Hydroxy-α-methylphenethylamine; 4-Hydroxyamphetamine; Norpholedrine; α-Methyltyramine

Latin name
Hydroxyamfetaminum

Trade names; preparations
Norveritol; Nov-Pholedrin; Oxamphetaminium; Oksamfetamin; Oxamfetamin; Paredrinex; Pulsoton; Paredrine; Paremyd; Pedrolon; Mycadrine

 

Chemical formulas

Molecular formula and structural formula of Hydroxyamphetamine:

 

C9H13NO

Mr = 151.209 g/mol

4-(2-Aminopropyl)phenol
SMILES: CC(CC1=CC=C(C=C1)O)N

 

Spectroscopic data:

SPLASH (mass spectra)
splash10-000i-0900000000-5bbd5ad65ba255afe471
splash10-000i-0900000000-159fe24f7c43f6361d17
SpectraBase (NMR, IR, FTIR, Raman, UV-Vis, MS ... spectra)
KyoReLog1kf
Human Metabolome Database (GC-MS, LC-MS/MS spectra, NMR)
HMDB0060765

Calculated NMR spectrum (Predict Spectra via NMRDB)
1H NMR Spektrum, 13C NMR Spektrum.

 

Percentage and isotopic composition:

Mass-related elemental composition and isotope proportions of the compound Hydroxyamphetamine - C9H13NO - calculated based on molecular mass.

Symbol
Element E
Number x
of atoms Ex
Data of the element
and isotopes *
Percentages
of isotopes
Percentage of
Ex in formula mass
C
Carbon
9 Ar = 12.011 u
ΣAr = 108.099 u
12C: 12 u [98,94 %]
14C: 14.00324 u [<< 1 %]
13C: 13.00335 u [1,06 %]
 
12C: 70.732 %
14C: trace
13C: 0.75779 %
71.4898 %H
Hydrogen
13 Ar = 1.008 u
ΣAr = 13.104 u
3H: 3.01605 u [<< 1 %]
1H: 1.00783 u [99,99 %]
2H: 2.0141 u [0,01 %]
 
3H: trace
1H: 8.66528 %
2H: 0.00087 %
8.6662 %N
Nitrogen
1ΣAr = 14.007 u
14N: 14.00307 u [99,6205 %]
15N: 15.00011 u [0,3795 %]
 
14N: 9.22818 %
15N: 0.03515 %
9.2633 %O
Oxygen
1ΣAr = 15.999 u
16O: 15.99491 u [99,757 %]
17O: 16.99913 u [0,03835 %]
18O: 17.99916 u [0,205 %]
 
16O: 10.55501 %
17O: 0.00406 %
18O: 0.02169 %
10.5807 %

*) The third column lists the atomic masses or isotope masses of the elements involved and - in square brackets - the natural isotope composition.

 

More calculated data

The molar mass is M = 151.209 grams per mole.

The amount of substance in one kilogram of the substance is n = 6.613 mol.

The amount of substance in one gram of the substance is n = 0.007 mol.

Monoisotopic mass: 151.09971404185 Da - related to 12C91H1314N16O.

 

Hydroxyamphetamine as Active Ingredient

International Non-Proprietary Name (INN): Hydroxyamfetamine. Latin name: Hydroxyamfetaminum.

Hydroxyamphetamine is a sympathomimetic that, in the form of the salt hydroxyamphetamine hydrobromide, was used in eye drops to dilate the pupils during eye examinations - also in combination with other substances such as tropicamide.

For detailed information on the active ingredient, see: DrugBank DB09352, NCI Thesaurus C61787.

 

Hazard warnings according to GHS

(General information without guarantee of accuracy and completeness! The information does not replace the chemical safety data sheet or a risk assessment, but rather provides a general overview of the risk posed by the hazardous substance.

Signal word: Danger

GHS hazard statements (H phrases):


H302
Harmful if swallowed

H315
Causes skin irritation

H318
Causes serious eye damage

H335
May cause respiratory irritation

Labeling in the EU: See ECHA Substance Infocard 100.002.866.


Note: The labeling requirement according to the CLP Regulation (EU) does not apply, among other things, to certain substances and mixtures for end users that are in the form of finished products, such as pharmaceuticals, veterinary drugs, cosmetics, certain medical products and medical devices, food or feed, as well as certain Food additives or flavorings. Special legal regulations may need to be adhered to here.

 

External Sources

PubChem:ID 3651ChemSpider:ID 3525UNII of the FDA (USA):Unique Ingredient Identifier FQR280JW2NEPA CompTox Chemicals Dashboard:DTXSID3023134Other CAS RN:1518-86-1 (also used, outdated or deleted registration numbers)

 

Manufacturers and Sources of Supply

The table below lists producers and suppliers of Hydroxyamphetamine as a commercial chemical for laboratories, research, industry and production with the corresponding contact details.

 

Literature Sources

[0] - Specialist and research articles in scientific journals via PubMed: Hydroxyamphetamine.

 


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Last update: 2026-02-11


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