Lutetium-177

Properties and data of the isotope ¹⁷⁷Lu.

Contents

General Data

Radioactive Decay

Radiation emissions

Parent Nuclides

Use in Medicine

Isotones und Isobares

Literature

See also: List of individual Lutetium isotopes (and general data sources).

General data

Name of the isotope:Lutetium-177; Lu-177Symbol:¹⁷⁷Lu or 17771LuMass number A:177 (= number of nucleons)Atomic number Z:71 (= number of protons)Neutrons N:106Nucleon pairing (Z - N):odd - evenNuclear ratio (N/Z ratio):1.4929577464789 (= neutron-proton ratio)Neutron excess (N-Z):35Isotopic mass:176.9437636(13) u (atomic weight of Lutetium-177)Nuclide mass:176.9048181 u (calculated nuclear mass without electrons)Mass excess:-52.38387 MeVMass defect:1.530294768 u (per nucleus)Nuclear binding energy:1425.46039462 MeV (per nucleus)
8.05344856 MeV (average binding energy per nucleon)Separation energy:S_N = 7.07289(16) MeV (first neutron)
S_P = 6.1816(12) MeV (first proton)Half-life:6.6443(9) dDecay constant λ:1.207431454334 × 10^-6 s^-1Specific activity α:4.131433123137 × 10⁺¹⁵ Bq g^-1
111660.35467939 Ci g^-1Spin and parity:
(nuclear angular momentum)7/2+Magnetic dipole moment:μ(μ_N) = +2.2384(14)Quadrupole moment Q:+3.39(3) barn (100 fm²)Nuclear g-factor:g_l = 0.63954285714286Charge radius:5.3815(305) femtometer fmYear of discovery:1945

Radioactive Decay

Half-life T_½ = 6.6443(9) d respectively 5.7406752 × 10⁵ seconds s.

Decay mode	Daughter	Probability	Decay energy	γ energy (intensity)
β^-	¹⁷⁷Hf	100 %	0.4968(8) MeV	siehe Tabelle

Lutetium-177 gamma radiation

E_γ	I_γ	Dose (MeV/Bq-s)
71.6418(6) keV	0.164(5) %	0.000117(4)
112.9498(4) keV	6.23(4) %	0.00704(5)
136.7245(5) keV	0.0465(4) %	0.0000636(5)
208.3662(4) keV	10.41(4) %	0.02169
249.6742(6) keV	0.1997(13) %	0.000499(3)
321.3159(6) keV	0.219(3) %	0.000702(10)

Parent Nuclides

Direct parent isotope is: ¹⁷⁷Yb.

Lutetium-177 as a Radionuclide in Medicine

Nuclear Isomers

Nuclear isomers or excited states with the activation energy in keV related to the ground state.

Nuclear Isomer	Excitation Energy	Half-life	Spin
^177mLu	970.1757(24) keV	160.4(3) d	23/2-
^177m1Lu	150.3984(10) keV	133.1(24) ns	9/2-
^177m2Lu	569.6721(15) keV	155(7) μs	1/2+
^177m7Lu	2771.7(5) keV	625(62) ns	33/2+
^177m8Lu	3530.4(6) keV	6(2) μs	39/2-

Isotones and Isobars

The following table shows the atomic nuclei that are isotonic (same neutron number N = 106) and isobaric (same nucleon number A = 177) with Lutetium-177. Naturally occurring isotopes are marked in green; light green = naturally occurring radionuclides.

Z	Isotone N = 106	Isobar A = 177
64	¹⁷⁰Gd
65	¹⁷¹Tb
66	¹⁷²Dy
67	¹⁷³Ho
68	¹⁷⁴Er	¹⁷⁷Er
69	¹⁷⁵Tm	¹⁷⁷Tm
70	¹⁷⁶Yb	¹⁷⁷Yb
71	¹⁷⁷Lu	¹⁷⁷Lu
72	¹⁷⁸Hf	¹⁷⁷Hf
73	¹⁷⁹Ta	¹⁷⁷Ta
74	¹⁸⁰W	¹⁷⁷W
75	¹⁸¹Re	¹⁷⁷Re
76	¹⁸²Os	¹⁷⁷Os
77	¹⁸³Ir	¹⁷⁷Ir
78	¹⁸⁴Pt	¹⁷⁷Pt
79	¹⁸⁵Au	¹⁷⁷Au
80	¹⁸⁶Hg	¹⁷⁷Hg
81	¹⁸⁷Tl	¹⁷⁷Tl
82	¹⁸⁸Pb
83	¹⁸⁹Bi
84	¹⁹⁰Po
85	¹⁹¹At

External data and identifiers

CAS:14265-75-9InChI Key:OHSVLFRHMCKCQY-NJFSPNSNSA-NSMILES:[177Lu]PubChem:ID 161046Adopted Levels, Gammas:NuDat 177Lu

Literature and References

[1] - Ashutosh Dash et al.:
Production of ¹⁷⁷Lu for Targeted Radionuclide Therapy: Available Options.
In: Nuclear Medicine and Molecular Imaging, (2015), DOI 10.1007/s13139-014-0315-z.

[2] - R. A. Kuznetsov, K. S. Bobrovskaya, V. V. Svetukhin, A. N. Fomin, A. V. Zhukov:
Production of Lutetium-177: Process Aspects.
In: Radiochemistry, (2019), DOI 10.1134/S1066362219040015.

[3] - Rupali Bhardwaj et al.:
Modelling of the ^177mLu/¹⁷⁷Lu radionuclide generator.
In: Applied Radiation and Isotopes, (2020), DOI 10.1016/j.apradiso.2020.109261.

[4] - W. V. Vogel, S. C. van der Marck, M. W. J. Versleijen:
Challenges and future options for the production of lutetium-177.
In: European Journal of Nuclear Medicine and Molecular Imaging, (2021), DOI 10.1007/s00259-021-05392-2.